Pipeline
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CLZ001
First-in-Class Anti-PROX1 Antibody
Targeting retinal regeneration through PROX1 neutralization
Remove Bad Homeoproteins
CLZ001 is a high-affinity anti-PROX1 antibody designed
to trigger endogenous retinal regeneration.
It targets extracellular PROX1 proteins, a key inhibitory factor
that suppresses tissue repair and regeneration.
By neutralizing extracellular PROX1,
CLZ001 reactivates dormant Müller glia regenerative pathways
and offers a novel approach to restoring vision.
PROX 1
Target Molecule
AMD / RP
Lead Programs
Expanding Target Diseases
Future
PIPELINE
Vision Loss Continues to Progress
Advancing innovative therapies through two complementary homeoprotein strategies.
CLZ001 Wet-AMD
Lead Optimization
CLZ002 RP
Preclinical
CLZ002 RP
Target Validation
CLZ002 RP
Target Validation